Ignet

Gene Pair: GHR, IGF1

Related Sentences

#	PMID	Sentence
1	3053958	Insulin can regulate IGF-I production, acting on the GH receptor or at a post-receptor site.
2	8016174	IGF-I may be a regulatory factor for serum GHBP activity in man.
3	8091976	We have determined GHBP activity in two cases of poorly controlled IDDM with low height velocity in relation to metabolic control in order to determine the mechanism of resistance to GH in this condition, as indicated by low levels of GH-dependent growth factor IGF-I in the face of high serum GH levels.
4	8091976	GHBP activity was within the normal range in two cases of IDDM with slow height velocity, low IGF-I and high hemoglobin-A1.
5	11422104	IGF-I and IGF-I SDS increased significantly at 1 and 3 months (P < 0.001) after commencing GHR.
6	17573420	The GHR fl/d3 genotype modulates the relationship between GH and IGF-1 concentrations in patients presenting with acromegaly.
7	17537658	In the larger subset of T2DM, GHR(d3) was associated with higher CRP levels as well as age adjusted IGF-I, with a trend of higher C-peptide secretion and impaired lipid levels, indicating a phenotype with metabolic disorder when compared to the GHR(fl/fl) T2DM subjects.
8	17534717	Pegvisomant, a growth hormone receptor antagonist, suppresses IGF-1 levels into the normal range in over ninety percent of patients.
9	22034225	GH and IGF-I exert their biological effects through binding to respective receptors (GHR and IGF-IR) and subsequently engaging downstream signaling pathways.