Ignet

Gene Pair: IDDM2, TAP1

Related Sentences

#	PMID	Sentence
1	8248212	These data provide new limits for IDDM susceptibility to the 190-kb interval between TAP1 and HLA-DQB1.
2	7578413	The aims of this project were to determine if Tap genes could be implicated in the defective class I expression associated with IDDM by using a novel Epstein-Barr virus (EBV)-mediated gene transfer system to introduce a cloned, normal Tap-2 or Tap-1 gene into B cell lines from normal and IDDM patients and analyzing the effect on conformationally dependent class I expression.
3	7578413	B cells from another 40% of IDDM patients responded to Tap-1 gene transfer.
4	7578413	These effects were specific because B cells from normal individuals did not respond to Tap-1 or Tap-2 gene transfer with increased class I expression, and B cells from IDDM patients responding to Tap-2 gene transfer did not respond to Tap-1 gene transfer and vice versa.