Ignet

Gene Pair: IGF1R, HSPE1

Related Sentences

#	PMID	Sentence
1	12970367	We have investigated the effects of two heat shock proteins, Hsp10 and Hsp60, on insulin-like growth factor-1 receptor (IGF-1R) signaling in cardiac muscle cells.
2	12970367	Thus, Hsp10 and Hsp60 overexpression increased the number of functioning receptors and amplified activation of IGF-1R signaling.
3	12970367	Using cycloheximide to inhibit protein synthesis did not alter the effect of Hsp60 on IGF-1R signaling, and IGF-1R mRNA levels were not up-regulated by Hsp10 or Hsp60.
4	12970367	These data indicate that Hsp10 and Hsp60 can modulate IGF-1R signaling through post-translational modification.