# |
PMID |
Sentence |
1 |
17915193
|
Insulin treatment may attenuate the impairment of Bcrp expression and function induced by diabetes.
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2 |
17915193
|
All results gave a conclusion that STZ-induced DM may induce the impairment of function and expression of Bcrp in brain cortex, and lower levels of insulin may mainly contribute to Bcrp dysfunction in brain.
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3 |
21602604
|
The aim of this study was to investigate the role of insulin in the regulation of breast cancer resistance protein (BCRP) function and expression using primary cultured rat brain microvessel endothelial cells (rBMECs) as an in vitro model of the blood brain barrier (BBB).
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4 |
21602604
|
Further results showed that insulin down-regulated the function and expression of BCRP in rBMECs in a concentration-dependent manner.
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5 |
21602604
|
These results indicate that insulin suppressed the function and expression of BCRPs in rBMEC primary cultures.
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