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Gene Pair Information
Gene Pair: INS, DUSP1
Related Sentences
# |
PMID |
Sentence |
1 |
12176727
|
Insulin inhibition of MAPK was accompanied by a rapid induction of MAPK phosphatase (MKP-1), which inactivates MAPKs by dephosphorylation.
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2 |
12176727
|
Expression of antisense MKP-1 RNA prevented insulin's inhibitory effect and restored PDGF-directed VSMC migration and MAPK phosphorylation.
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3 |
12176727
|
We conclude that insulin inhibition of VSMC migration may be mediated in part by NO/cGMP/cGK Ialpha induction of MKP-1 and consequent inactivation of MAPKs.
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