Ignet

Gene Pair: INS, FTO

Related Sentences

#	PMID	Sentence
1	19625203	The aim of the present study was to assess the effect of FTO variation on obesity, insulin sensitivity, and metabolic and hormonal profiles in PCOS.
2	19763711	We tested for site-specific differences in FTO gene expression in subcutaneous and visceral adipose tissue (SAT and VAT, respectively) from individuals with and without type 2 diabetes mellitus (T2D) and the relationships between fasting glucose, in vivo insulin action, and measures of adiposity with FTO gene expression in adipose tissue.
3	19763711	Insulin action did not relate to SAT or VAT FTO mRNA expression.
4	20813088	Some authors showed that FTO gene polymorphism influences the food intake, energy expanditure and insulin resistance.
5	20943749	Interestingly, rosiglitazone treatment improved insulin sensitivity and reduced FTO expression in muscle from type 2 diabetic patients.
6	21070190	Taken together, these results suggest that the FTO protein may play a hitherto unrecognized role in the control of first-phase insulin secretion in pancreatic ?-cells.
7	21919686	This study also established that SNP in intron 1 of FTO (rs17817449) are strongly associated with several measures of adiposity and are also associated with plasma insulin, insulin resistance, percentage body fat and fat mass.