Ignet

Gene Pair: INS, KIF5B

Related Sentences

#	PMID	Sentence
1	20870970	Suppression of Kinesin-1 by antisense oligonucleotides, or overexpression of dominant-negative acting kinesin heavy chain, has been reported to affect the sustained phase of glucose-stimulated insulin secretion in ?-cells in vitro.
2	20870970	However, compared with controls, pancreas of Kif5b(fl/)?:RIP2-Cre mice exhibited both reduced islet size and increased islet number, concomitant with an increased insulin vesicle density in ?-cells.
3	20870970	In addition to being essential for maintaining glucose homeostasis and regulating ?-cell function, Kif5b may be involved in ?-cell development by regulating ?-cell proliferation and insulin vesicle synthesis.