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Gene Pair Information
Gene Pair: INS, MAP3K14
Related Sentences
# |
PMID |
Sentence |
1 |
21846802
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After weight loss, skeletal muscle NIK protein was significantly reduced in association with increased plasma adiponectin and enhanced AMP kinase phosphorylation and insulin sensitivity in obese subjects.
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2 |
21846802
|
Overexpression of NIK kinase-dead dominant negative did not affect insulin-stimulated glucose uptake.
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3 |
21846802
|
Adiponectin treatment inhibited NIK-induced NF-?B activation and restored insulin sensitivity by restoring PI3 kinase activation and subsequent Akt phosphorylation.
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4 |
21846802
|
These results indicate that NIK induces insulin resistance and further indicate that adiponectin exerts its insulin-sensitizing effect by suppressing NIK-induced skeletal muscle inflammation.
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