Ignet

Gene Pair Information

Gene Pair: INS, ME1

Related Sentences

#	PMID	Sentence
1	729537	Insulin appeared to have a specific effect on the activities of glucokinase, ATP-citrate lyase, malic enzyme, and glucose-6-P-dehydrogenase.
2	3284417	Similarly, the activity of the hepatic lipogenic enzyme, malic enzyme, increased at initial insulin dosages and reached maximal levels at 2 + 2.
3	2663078	Insulin action on regulation of hepatic malic enzyme has been investigated in comparison with fructose, using streptozotocin-induced diabetic rats.
4	2663078	On the other hand, by feeding a high-fructose diet to diabetic rats, the malic enzyme mRNA concentration was considerably increased, though with a delayed peaking in comparison with the insulin-treated animals, whereas the transcriptional rate was not significantly increased.
5	2663078	These results suggest that insulin is required in both the translational and transcriptional regulation of malic enzyme.
6	2663571	However, since insulin-mediated regulatory processes have been shown to be tissue specific, we decided to examine malic enzyme activity in the epididymal fat pads of normal, diabetic, and insulin-treated normal and diabetic rats.
7	2663571	Insulin treatment of both normal and diabetic rats resulted in an increase in epididymal fat pad malic enzyme activity due to increases in both enzyme quantity and specific activity.
8	2028716	We examined the effects of T3 and insulin on the activity of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and cytosolic malic enzyme in control, thyroidectomized, thyroidectomized food-restricted, and thyroidectomized diabetic rats.
9	2028716	The data suggest that insulin may act on malic enzyme synthesis through its general stimulatory effect on protein synthesis, or by antagonizing factors that inhibit the induction of this enzyme.
10	1381373	The class I response to TSH, serum, insulin, IGF-I, or hydrocortisone is specific, in that the same agents do not similarly affect TSH receptor, thyroglobulin, thyroid peroxidase, malic enzyme, or beta-actin RNA levels.
11	7854353	The malic enzyme (ME) gene, which encodes an important lipogenic enzyme, was used to investigate insulin regulation of gene expression.