Ignet

Gene Pair Information

Gene Pair: INS, NAMPT

Related Sentences

#	PMID	Sentence
1	15952917	Among those, adiponectin, visfatin and omentin appear as insulin-sensitising adipocytokines, whereas TNF-alpha, IL-6 and resistin induce insulin resistance.
2	16394088	We also examined whether visfatin is regulated by thiazolidinediones and, thus, can contribute to the ability of these agents to improve insulin sensitivity.
3	16720654	Elevation of free fatty acid induced a condition of insulin resistance but did not affect either circulating visfatin or its mRNA.
4	17003355	We hypothesized that visfatin is associated with insulin secretion in humans.
5	17003355	In nondiabetic subjects, circulating visfatin (enzyme immunoassay) was independently associated with insulin secretion (acute insulin response to glucose [AIRg] from intravenous glucose tolerance tests) but not with insulin sensitivity (Si) or other metabolic or anthropometric parameters, and AIRg alone explained 8% of visfatin variance (beta = -0.29, P = 0.001).
6	18704364	Reductions of insulin resistance (measured by homeostasis model assessment of insulin resistance) were independently associated with changes of glucagon, visfatin and PP.
7	19940327	Adipose tissue produces multiple cytokines(TNF-alpha, IL-6, PAI-1, CRP, angiotensinogen, leptin, adiponectin, visfatin, apelin, resistin)which decrease insulin sensitivity and induce inflammatory processes, endothelial dysfunction,and atherosclerosis.
8	19184512	In group I, visfatin correlated with insulin concentration (r = 0.428, P = 0.023), HOMA-IR with esRAGE (r = -0.374, P = 0.049).
9	19184512	Insulin resistance seems to be a link between esRAGE and visfatin in IHD diabetics.
10	20956860	Adiponectin and visfatin are two cytokines which are considered to be possible links between obesity, insulin resistance and the metabolic syndrome.
11	20699433	The coinfusion of insulin led to a total elimination of the increase in NOM, free fatty acids, and TBARS and a significant reduction in ROS generation by PMNLs and plasma MIF, visfatin, and myoglobin concentrations.
12	21484571	Nampt plays an important role in the regulation of insulin secretion insulin secretion in pancreatic ?-cells.
13	21325104	Visfatin and adiponectin are produced by adipose tissue and have opposite effects on insulin resistance.
14	21694775	We then assessed the effects of an insulin sensitizer, rosiglitazone (RSG), in treatment na�ve T2DM subjects, on circulating visfatin levels.
15	21694775	Our findings showed that visfatin was reduced post-RSG treatment [vs. pre-treatment (p<0.05)] accompanied by a reduction in HOMA-IR*, thus implicating a role for insulin in visfatin regulation.
16	21694775	Following insulin (Ins) and RSG treatment, our in vitro findings highlighted that insulin (100 nM), alone, upregulated visfatin protein expression whereas, in combination with RSG (10 nM), it reduced visfatin, IKK?* and p-JNK1/2*.
17	21694775	These data highlight visfatin's regulation by insulin and RSG, potentially acting through NF-?B and JNK mechanisms, with only rh IL-6 modestly affecting visfatin regulation.
18	21939650	Plasma visfatin and RBP-4 concentrations correlated with BMI, waist/hip ratio, insulin and homeostatic model assessment insulin resistance (HOMA(IR)).