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Gene Pair Information

Gene Pair: INS, ODC1

Related Sentences

# PMID Sentence
1 6445842 Insulin treatment within 10 h of the SZ injection prevented the increase of ODC activity; however, insulin given after enzyme activity had increased did not restore ODC activity to control levels.
2 7018971 Addition of insulin and amino acids had no effect; however, 50% rat serum increased ODC activity four- to seven-fold after the initial decrease.
3 7018971 These findings suggest that insulin modulates the synthesis of ODC via production of a second circulating factor, the activity of which is diminished in serum of diabetic rats.
4 7026548 When glucagon or insulin was given to pancreatectomized rats, dietary induction of ODC was restored to a level found in normal rats.
5 7026548 These results suggest that increased influx of amino acids into liver is a critical factor for dietary induction of ODC and that both glucagon and insulin play a role in stimulating amino acid influx.
6 2146735 We measured ODC activity, of ventricular homogenates obtained from diabetic SHR and nonhypertensive WKY rats, with and without chronic treatment with insulin or triiodothyronine (T3).
7 2146735 Both T3 and insulin therapy prevented the decline in ventricular ODC activity in both strains, although only the effect of insulin was correlated with LVW.
8 1511780 However, in muscle from diabetic animals the ODC activity declined steadily during the 14 days to 34% of control values (P less than 0.01), and insulin treatment completely normalized the ODC activity in muscle.
9 8447376 Insulin treatment normalized renal ODC activity, whereas DFMO treatment totally inhibited the kidney ODC activity.
10 8447376 Insulin treatment normalized both kidney weight and kidney ODC activity.