Ignet

Gene Pair: INS, PCK1

Related Sentences

#	PMID	Sentence
1	16282543	We previously showed that a -232C>G promoter polymorphism within a cis-acting element required for basal and cAMP-mediated PCK1 gene transcription results in loss of negative regulation by insulin, contributing to worsened metabolic control in the context of insulin resistance.
2	20484139	The increased insulin and IL-6 signaling resulted in enhanced suppression of G6pc and Pck1 mRNA.
3	16126724	In liver, insulin suppresses gluconeogenesis by inhibiting the transcriptions of phosphoenolpyruvate carboxylase (PEPCK) and glucose-6-phosphatase (G6Pase) genes.