Ignet

Gene Pair: INS, PKN1

Related Sentences

#	PMID	Sentence
1	21969371	Mimicking this, islets from PAK1(-/-) knock-out mice exhibited profound defects in the second/sustained-phase of insulin secretion.
2	21969371	Exacerbating this, the PAK1(-/-) knock-out mice also exhibited peripheral insulin resistance.
3	21969371	Insulin resistance was coupled to ablation of insulin-stimulated GLUT4 translocation in skeletal muscle from PAK1(-/-) knock-out mice, and in sharp contrast to islet beta cells, skeletal muscle PAK1 loss was underscored by defective cofilin phosphorylation but normal ERK1/2 activation.