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Gene Pair Information

Gene Pair: INS, PRKCB1

Related Sentences

# PMID Sentence
1 8922537 However, PKC beta I mRNA was decreased for up to 60 min and then maintained at under the basal level during stimulation with insulin and TPA.
2 16505232 Thus, activation of PKCbeta in endothelial cells and vascular tissue inhibits Akt activation by insulin and VEGF, inhibits Akt-dependent eNOS regulation by insulin, and causes endothelial dysfunction in obesity-associated insulin resistance.
3 18241357 Akt/PKB is associated with a downstream insulin signaling, and PKCbeta attenuates insulin-stimulated Akt phosphorylation.
4 20179320 Here we show that protein kinase C beta (PKCbeta) is a key mediator of insulin-mediated activation of hepatic SREBP-1c and its target lipogenic genes.
5 20179320 The effect of PKCbeta inhibition was cancelled in insulin depletion by streptozotocin (STZ) treatment of mice.