Ignet

Gene Pair: INS, SMAD3

Related Sentences

#	PMID	Sentence
1	18951876	In this study, human insulin promoter was activated by Smad2, Smad3 and the pancreatic and duodenal homeobox factor-1 (PDX-1) in the ALK7 pathway.
2	19265200	Transduction of adenoviral Smad3 into primary human and non-human primate islets suppresses insulin content, whereas, dominant-negative Smad3 enhances insulin levels.
3	21270259	Transforming growth factor-?/Smad3 signaling has been implicated in various metabolic processes, including adipogenesis, insulin expression, and pancreatic ?-cell function.
4	21270259	Smad3-knockout mice exhibited diminished adiposity with improved glucose tolerance and insulin sensitivity.