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Gene Pair Information
Gene Pair: ISL1, MYC
Related Sentences
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PMID |
Sentence |
1 |
21829621
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Using HIT-T15 and primary adult islet cells as cell models, we show that ISL1 promoted adult pancreatic islet cell proliferation with increased c-Myc and CyclinD1 transcription, while knockdown of ISL1 increased the proportion of cells in G(1) phase and decreased the proportion of cells in G(2)/M and S phases.
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2 |
21829621
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Further investigation shows that ISL1 activated both c-Myc and CyclinD1 transcription through direct binding on their promoters.
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