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Gene Pair Information

Gene Pair: ISL1, MYC

Related Sentences

# PMID Sentence
1 21829621 Using HIT-T15 and primary adult islet cells as cell models, we show that ISL1 promoted adult pancreatic islet cell proliferation with increased c-Myc and CyclinD1 transcription, while knockdown of ISL1 increased the proportion of cells in G(1) phase and decreased the proportion of cells in G(2)/M and S phases.
2 21829621 Further investigation shows that ISL1 activated both c-Myc and CyclinD1 transcription through direct binding on their promoters.