Ignet

Gene Pair: KCNJ11, ABCC8

Related Sentences

#	PMID	Sentence
1	21411514	Congenital hyperinsulinism in infancy (CHI) is characterized by unregulated insulin secretion from pancreatic ?-cells; severe forms are associated with defects in ABCC8 and KCNJ11 genes encoding sulfonylurea receptor 1 (SUR1) and Kir6.2 subunits, which form ATP-sensitive K(+) (K(ATP)) channels in ?-cells.
2	15631623	Molecular analyses have demonstrated that Foxa2 is an important regulator of the genes encoding Sur1, Kir6.2 and Schad (short chain L-3-hydroxyacyl-CoA dehydrogenase), mutation of which causes PHHI in humans.