Ignet

Gene Pair: LEP, COL1A1

Related Sentences

#	PMID	Sentence
1	11260392	In db/db mesangial cells, leptin increased 2-deoxy-D-glucose (2DOG) uptake dose dependently and stimulated gene expression of TGF-beta type II receptor (TbetaRII) and alpha1(I) collagen, but not TGF-beta1.
2	11260392	Mesangial cells pretreated with leptin exhibited increased responsiveness to exogenous TGF-beta1, as evidenced by a greater production of type I collagen protein in leptin-pretreated cells exposed to low-dose TGF-beta1 (0.5 ng/mL).
3	11260392	The addition of both TGF-beta1 (2 ng/mL) and leptin (100 ng/mL) increased type I collagen production more than addition of either TGF-beta1 or leptin alone.
4	11260392	Leptin increases glucose uptake and type I collagen in db/db mesangial cells through a PI-3K-dependent pathway.