Ignet

Gene Pair: LEP, MMP2

Related Sentences

#	PMID	Sentence
1	15983226	Incubation of HASMCs with leptin enhanced the proliferation and MMP-2 expression in these cells and increased the generation of intracellular reactive oxygen species (ROS).
2	15983226	In HASMCs, leptin induced PKC, extracellular signal-regulated kinase (ERK)1/2, and nuclear factor-kappaB (NF-kappaB) activation and inhibition of these signaling pathways abrogated HASMC proliferation and MMP-2 expression induced by this hormone.
3	15983226	Metformin also inhibited the effect of leptin on HASMC proliferation and MMP-2 expression.