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Gene Pair Information
Gene Pair: MAPK14, IL8
Related Sentences
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PMID |
Sentence |
1 |
15145956
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Inhibition of the p38 pathway using 5 microm SB203580 significantly reduced glucose-mediated IL-8 mRNA production by 60%.
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2 |
15145956
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Thus, glucose-stimulated monocyte adhesion is primarily regulated through phosphorylation of p38 with subsequent activation of AP-1, leading to IL-8 production.
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3 |
15145956
|
Taken together, these data indicate that chronic elevated glucose in diabetes activates the p38 MAP kinase pathway to increase inflammatory IL-8 gene induction and monocyte/endothelial adhesion.
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