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Gene Pair Information

Gene Pair: MTNR1B, INS

Related Sentences

# PMID Sentence
1 20185807 Abnormalities in early insulin secretion were suggested in glucose-raising allele carriers at MTNR1B, GCK, FADS1, DGKB, and PROX1 (lower insulinogenic index; no association with proinsulin or insulin sensitivity).
2 21585522 On the basis of a specific radioimmunoassay, insulin secretion was found to be more strongly reduced in the clones expressing hMT2 than in INS-1 controls, when incubated with 1 or 100 nm melatonin.
3 21711391 Previously reported association between MTNR1B variants (rs10830963, rs4753426) and oral glucose tolerance test-derived indices of ?-cell function (homeostasis model assessment-B, P = 3.7 × 10?? and P = 0.004, respectively), as well as insulin (fasting insulin: P=2×10?³ and P=0.02; 30-min insulin: P = 2.1 × 10?? and P=0.03, respectively) and fasting glucose (rs10830963, P=1.2×10??) parameters could be replicated in the present study.