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Gene Pair Information
Gene Pair: NOTCH1, NPHS1
Related Sentences
# |
PMID |
Sentence |
1 |
20522599
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After use of pharmacological modulators or specific shRNA knockdown strategies, inhibition of Notch-1 signaling significantly abrogated VEGF activation and nephrin repression in HG-stressed cells and ameliorated proteinuria in the diabetic kidney.
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2 |
20522599
|
Our findings suggest that upregulation of Notch-1 signaling in HG-treated renal podocytes induces VEGF expression and subsequent nephrin repression and apoptosis.
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