Ignet

Gene Pair: NPPB, YY1

Related Sentences

#	PMID	Sentence
1	19139378	Here we demonstrate that both basal- and endothelin-1-dependent stimulation of human (h) BNP gene transcription requires the presence of an intact Yin Yang 1 (YY1) binding site positioned at -62 bp relative to the transcription start site.
2	19139378	YY1 was shown to associate with histone deacetylase 2, and histone deacetylase 2 was shown to associate directly with the hBNP promoter in the intact cell.
3	19139378	Collectively these findings demonstrate that YY1 plays an important role in regulating the transcriptional activity of the hBNP gene promoter.
4	19139378	These data suggest a model in which YY1 activates hBNP transcription through interaction with histone deacetylase 2.