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PMID |
Sentence |
1 |
6445842
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Insulin treatment within 10 h of the SZ injection prevented the increase of ODC activity; however, insulin given after enzyme activity had increased did not restore ODC activity to control levels.
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2 |
7018971
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Addition of insulin and amino acids had no effect; however, 50% rat serum increased ODC activity four- to seven-fold after the initial decrease.
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3 |
7018971
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These findings suggest that insulin modulates the synthesis of ODC via production of a second circulating factor, the activity of which is diminished in serum of diabetic rats.
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4 |
7026548
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When glucagon or insulin was given to pancreatectomized rats, dietary induction of ODC was restored to a level found in normal rats.
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5 |
7026548
|
These results suggest that increased influx of amino acids into liver is a critical factor for dietary induction of ODC and that both glucagon and insulin play a role in stimulating amino acid influx.
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6 |
2146735
|
We measured ODC activity, of ventricular homogenates obtained from diabetic SHR and nonhypertensive WKY rats, with and without chronic treatment with insulin or triiodothyronine (T3).
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7 |
2146735
|
Both T3 and insulin therapy prevented the decline in ventricular ODC activity in both strains, although only the effect of insulin was correlated with LVW.
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8 |
1511780
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However, in muscle from diabetic animals the ODC activity declined steadily during the 14 days to 34% of control values (P less than 0.01), and insulin treatment completely normalized the ODC activity in muscle.
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9 |
8447376
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Insulin treatment normalized renal ODC activity, whereas DFMO treatment totally inhibited the kidney ODC activity.
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10 |
8447376
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Insulin treatment normalized both kidney weight and kidney ODC activity.
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