# |
PMID |
Sentence |
1 |
7021386
|
Pyruvate dehydrogenase complex activity and its regulating factors were measured in diabetic mice in a starved or unstarved state.
|
2 |
7021386
|
Both in starved and unstarved groups of normal mice, pyruvate dehydrogenase complex activity increased equally by insulin administration.
|
3 |
7021386
|
We found that unlike the normal mice, not only the previously known regulating mechanism but also other factors affected the pyruvate dehydrogenase complex activity in the diabetic mice.
|
4 |
12099888
|
In insulin deficiency, increased lipid delivery and oxidation suppress skeletal-muscle glucose oxidation by inhibiting pyruvate dehydrogenase complex (PDC) activity via enhanced protein expression of pyruvate dehydrogenase kinase (PDK) isoform 4, which phosphorylates (and inactivates) PDC.
|
5 |
15967803
|
Phosphorylation of pyruvate dehydrogenase by the pyruvate dehydrogenase kinases (PDK) inhibits pyruvate dehydrogenase complex activity.
|
6 |
19366875
|
Decreased pyruvate dehydrogenase complex activity was also observed in lipid- and insulin-infused animals (43%).
|