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Gene Pair Information

Gene Pair: PDX1, GIP

Related Sentences

# PMID Sentence
1 18593849 We investigated whether Pax6 and Pdx1 activate the human GIP promoter in control IEC-6 cells and GIP-expressing STC-1 cells.
2 18593849 GIP promoter activity was enhanced in IEC-6 cells by exogenous Pax6 or Pdx1 and diminished in STC-1 cells by inhibition of endogenous Pax6 or Pdx1 by dominant-negative forms.
3 18593849 EMSA studies indicated that Pax6 and Pdx1 bind to this proximal sequence of the human GIP promoter.
4 18593849 Our findings indicate that concomitant expression of Pax6 and Pdx1 is important for GIP expression.
5 21270265 Inhibition of GIP or its receptor also led to a decrease in the number of Pdx-1-positive and sox9-positive cells in the cultured embryonic pancreas.