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Gene Pair Information
Gene Pair: POMC, STAT3
Related Sentences
# |
PMID |
Sentence |
1 |
17023536
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We find that Pomc expression is diminished in the mutant mice, suggesting that Stat3 is required for Pomc transcription.
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2 |
17023536
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These results demonstrate a requirement for Stat3 in transcriptional regulation of Pomc but indicate that this circuit is only one of several components that underlie the neuronal response to leptin and the role of Stat3 in that response.
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3 |
20068134
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Upregulation of Socs3 in POMC neurons leads to impairment of STAT3 and mammalian target of rapamycin (mTOR)-S6K-S6 signaling, with subsequent leptin resistance, obesity, and glucose intolerance.
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