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Gene Pair Information
Gene Pair: PPARA, PDK4
Related Sentences
# |
PMID |
Sentence |
1 |
12099888
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We evaluated the participation of PPARalpha in regulating PDK4 protein expression in slow oxidative (SO) skeletal muscle (soleus) and fast oxidative-glycolytic (FOG) skeletal muscle (anterior tibialis) containing a high proportion of oxidative fibres.
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2 |
12099888
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In the fed state, acute (24 h) activation of PPARalpha by WY14,643 in vivo failed to modify PDK4 protein expression in soleus, but modestly enhanced PDK4 protein expression in anterior tibialis.
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3 |
12435272
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Enhanced expression of PDK4, but not PDK2, occurs in part via a mechanism involving PPAR-alpha.
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4 |
12435272
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Administration of the selective PPAR-alpha activator WY14,643 significantly increased PDK4 protein to a similar extent in both control and high-fat-fed rats, but WY14,643 treatment and hyperthyroidism did not have additive effects on hepatic PDK4 protein expression.
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5 |
12435272
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The results indicate that hepatic PDK4 up-regulation can be achieved by heterodimerization of either PPARalpha or TR with the RXR receptor and that effects of PPARalpha activation on hepatic PDK2 and PDK4 expression favour a switch towards preferential expression of PDK4.
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6 |
15292029
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Specific activation of PPAR alpha with WY-14643 rapidly induced pdk4 expression in heart and soleus muscle.
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