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Gene Pair Information

Gene Pair: PPARGC1A, UCP1

Related Sentences

# PMID Sentence
1 10603304 The expression of both mtDNA (by mtTFA) and nDNA for oxphos and UCP (by NRFs, etc.) is coordinated by a factor called PGC-1.
2 12807871 Peroxisome proliferator-activated receptor gamma (PPAR gamma) and PPAR gamma coactivator 1 alpha (PGC-1 alpha) activate mouse UCP1 gene transcription.
3 12807871 We show here that human PGC-1 alpha induced the activation of the human UCP1 promoter by PPAR gamma.
4 12807871 Adenovirus-mediated expression of human PGC-1 alpha increased the expression of UCP1, respiratory chain proteins, and fatty acid oxidation enzymes in human subcutaneous white adipocytes.
5 12807871 The PPAR gamma agonist rosiglitazone potentiated the effect of PGC-1 alpha on UCP1 expression and fatty acid oxidation.
6 12807871 UCP1 mRNA induction was shown in vivo by injection of the PGC-1 alpha adenovirus in mouse white fat.