Ignet

Gene Pair: PRKCZ, IRS2

Related Sentences

#	PMID	Sentence
1	18202124	In an in vitro kinase assay, purified recombinant PKC-zeta phosphorylated IRS-1, -3 and -4 but not IRS-2.
2	18202124	In cells overexpressing PKC-zeta there was marked inhibition of insulin-stimulated PI3K activity associated with IRS-1, -3 and -4 but not IRS-2.
3	18202124	That is, PI3K activity associated with IRS-2 in response to insulin was similar in control cells and cells overexpressing PKC-zeta.
4	18202124	The inability of PKC-zeta to phosphorylate IRS-2 may help determine specific functional roles for IRS-2.