Ignet

Gene Pair: RHOD, CCL2

Related Sentences

#	PMID	Sentence
1	20977889	Based on these data we infer that Y-27632 inhibits TNF-?-induced MCP-1 expression, secretion and function through inhibition of Rho-kinase and p38 MAPK activity.
2	21787749	In the present study, we investigated whether the small G protein RhoA, and its effector, Rho-kinase are involved in MCP-1 induction by thrombin in endothelial cells.
3	21787749	Y-27632, a specific Rho-kinase inhibitor, potently inhibited MCP-1 induction by thrombin.
4	21787749	Importantly, fasudil, a specific Rho-kinase inhibitor, attenuated MCP-1 gene expression in the aorta of db/db mice.
5	21787749	Y-27632 attenuated thrombin-mediated phosphorylation of p38MAPK and p65, indicating that Rho-kinase mediates thrombin-induced MCP-1 expression through p38MAPK and NF-?B activation.