Ignet

Gene Pair: SCN5A, AQP2

Related Sentences

#	PMID	Sentence
1	16159898	Semiquantitative confocal immunofluorescence microscopy of AQP2 immunolabeling showed reduced AQP2 expression in the apical plasma membrane domain in connecting tubule (CNT) and initial cortical collecting ducts (iCCD) in response to aldosterone-treated rats compared with rats treated with lithium only.
2	16159898	Spironolactone significantly increased apical AQP2 expression in the iCCD compared with rats treated with lithium only.
3	16159898	This study shows that aldosterone treatment perturbs diabetes insipidus and is associated with AQP2 redistribution in CNT and iCCD likely mediated by the spironolactone-sensitive mineralocorticoid receptor.