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Gene Pair Information

Gene Pair: SGK1, SLC2A1

Related Sentences

# PMID Sentence
1 16443776 GLUT1 contains a consensus site ((95)Ser) for phosphorylation by SGK1.
2 16443776 Tracer-flux studies in Xenopus oocytes and HEK-293 cells demonstrated that GLUT1 transport is enhanced by constitutively active (S422D)SGK1.
3 16443776 The effect requires the kinase catalytical activity since the inactive mutant (K127N)SGK1 failed to modulate GLUT1.
4 16443776 GLUT1 stimulation by (S422D)SGK1 is not due to de novo protein synthesis but rather to an increase of the transporter's abundance in the plasma membrane.
5 16443776 These observations suggest that SGK1 regulates GLUT1 and may contribute to or account for the PI3 kinase-dependent but PKB-independent stimulation of GLUT1 by insulin.