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Gene Pair Information

Gene Pair: SH2B1, JAK2

Related Sentences

# PMID Sentence
1 15767667 Consistent with previous reports, we further show that the SH2 domains of SH2-B and APS bind JAK2 at Tyr813.
2 15767667 At lower levels of SH2-B or APS expression, dimerization approximates two JAK2 molecules to induce transactivation.
3 20484460 In cultured cells, SH2B1 promotes leptin and insulin signaling by binding via its SH2 domain to phosphorylated tyrosines in Janus kinase 2 and the insulin receptor, respectively.