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Gene Pair Information

Gene Pair: SIRT1, PRKAA2

Related Sentences

# PMID Sentence
1 21733059 AMPK activates SIRT1 in liver and skeletal muscle.
2 21742060 In neurons, the nutrient excess associated with prolonged diabetes may trigger a switching off of AMP kinase (AMPK) and/or silent information regulator T1 (SIRT1) signaling leading to impaired peroxisome proliferator-activated receptor ? coactivator-1 (PGC-1?) expression/activity and diminished mitochondrial activity.
3 20929977 Parallel to this, we observed AMPK activation, PGC-1? deacetylation, and SIRT1 induction in trained wild-type mice.
4 20929977 CONCLUSIONS Chronic exercise induces mitochondrial biogenesis in wild-type mice, which may require intact AMPK activation by adipocytokines and involve SIRT1-dependent PGC-1? deacetylation.
5 21270273 The phosphorylation of 5'-AMP-activated kinase (AMPK) and expression of silent information regulator 1 (SIRT1) in the kidney were assessed by immunoblotting.
6 21270273 RSV neither modified AMPK activation nor SIRT1 expression in the kidney.
7 21241768 Different SIRT1 targets have been identified, including PTP1B, AMPK, FOXO, PGC-1? and IRS2.