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Gene Pair Information
Gene Pair: SIRT1, PRKAA2
Related Sentences
# |
PMID |
Sentence |
1 |
21733059
|
AMPK activates SIRT1 in liver and skeletal muscle.
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2 |
21742060
|
In neurons, the nutrient excess associated with prolonged diabetes may trigger a switching off of AMP kinase (AMPK) and/or silent information regulator T1 (SIRT1) signaling leading to impaired peroxisome proliferator-activated receptor ? coactivator-1 (PGC-1?) expression/activity and diminished mitochondrial activity.
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3 |
20929977
|
Parallel to this, we observed AMPK activation, PGC-1? deacetylation, and SIRT1 induction in trained wild-type mice.
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4 |
20929977
|
CONCLUSIONS Chronic exercise induces mitochondrial biogenesis in wild-type mice, which may require intact AMPK activation by adipocytokines and involve SIRT1-dependent PGC-1? deacetylation.
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5 |
21270273
|
The phosphorylation of 5'-AMP-activated kinase (AMPK) and expression of silent information regulator 1 (SIRT1) in the kidney were assessed by immunoblotting.
|
6 |
21270273
|
RSV neither modified AMPK activation nor SIRT1 expression in the kidney.
|
7 |
21241768
|
Different SIRT1 targets have been identified, including PTP1B, AMPK, FOXO, PGC-1? and IRS2.
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