Ignet

Gene Pair: SLC2A1, SGK1

Related Sentences

#	PMID	Sentence
1	16443776	GLUT1 contains a consensus site ((95)Ser) for phosphorylation by SGK1.
2	16443776	Tracer-flux studies in Xenopus oocytes and HEK-293 cells demonstrated that GLUT1 transport is enhanced by constitutively active (S422D)SGK1.
3	16443776	The effect requires the kinase catalytical activity since the inactive mutant (K127N)SGK1 failed to modulate GLUT1.
4	16443776	GLUT1 stimulation by (S422D)SGK1 is not due to de novo protein synthesis but rather to an increase of the transporter's abundance in the plasma membrane.
5	16443776	These observations suggest that SGK1 regulates GLUT1 and may contribute to or account for the PI3 kinase-dependent but PKB-independent stimulation of GLUT1 by insulin.