Ignet

Gene Pair: SLC2A4, EDN1

Related Sentences

#	PMID	Sentence
1	15919791	Furthermore, addition of exogenous PIP(2), but not PIP(3), restored insulin-regulated GLUT4 translocation and glucose transport impaired by ET-1.
2	16240321	Endothelin-1 (ET-1) disrupts insulin-regulated glucose transporter GLUT4 trafficking.
3	16240321	Since the negative consequence of chronic ET-1 exposure appears to be independent of signal disturbance along the insulin receptor substrate-1/phosphatidylinositol (PI) 3-kinase (PI3K)/Akt-2 pathway of insulin action, we tested if ET-1 altered GLUT4 regulation engaged by osmotic shock, a PI3K-independent stimulus that mimics insulin action.
4	16240321	Regulation of GLUT4 by hyperosmotic stress was impaired by ET-1.