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Gene Pair Information
Gene Pair: SNF1LK2, FASN
Related Sentences
# |
PMID |
Sentence |
1 |
18239551
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Electroporation was used to transiently transfect 3T3-L1 adipocytes with fatty acid synthase (FAS) promoter-driven luciferase construct to evaluate the effect of SIK2 on FAS transcription.
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2 |
18239551
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Overexpression of SIK2 repressed the expression of lipogenic genes, including FAS, acetyl CoA carboxylase 2 (ACC2), and stearoyl CoA desaturase 1 (SCD1), and reduced triglyceride content.
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3 |
18239551
|
Reduction of endogenous SIK2 expression through RNA interference increased the expression of FAS, ACC2, and SCD1.
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4 |
18239551
|
SIK2 inhibits the expression of FAS-promoter driven luciferase reporter gene, and this effect can be reversed by overexpression of constitutively active sterol regulatory element binding protein-1 (SREBP-1).
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