Ignet

Gene Pair: SOCS3, TRAF6

Related Sentences

#	PMID	Sentence
1	21249428	While SOCS-3 mRNA levels increased, plasma TNF? and IL-6 levels were also significantly higher in patients with type 2 diabetes. miR-146a expression was negatively correlated to glycated hemoglobin, insulin resistance, TRAF6, and NF?B mRNA levels and circulatory levels of TNF? and IL-6.
2	16543409	By coimmunoprecipitation, it was shown that SOCS-3 inhibited the association between TRAF6 and TAK1 and that SOCS-3 coimmunoprecipitated with TAK1 and TRAF6.
3	16543409	Because ubiquitination of TRAF6 is required for activation of TAK1, we analyzed the role of SOCS-3 on TRAF6 ubiquitination and found that SOCS-3 inhibited ubiquitin modification of TRAF6.