|
Gene Pair Information
Gene Pair: TNF, IRAK1BP1
Related Sentences
# |
PMID |
Sentence |
1 |
17079333
|
SIMPL (signaling molecule that associates with mouse Pelle-like kinase) is a component of a signaling pathway through which tumor necrosis factor-alpha (TNF-alpha) induces NF-kappaB-controlled gene transcription.
|
2 |
17079333
|
SIMPL interacts with the nuclear pool of the NF-kappaB subunit, p65, in a TNF-alpha-dependent manner to enhance p65-dependent gene transcription.
|
3 |
17079333
|
SIMPL mutants lacking sites of TNF-alpha-enhanced phosphorylation impaired nuclear localization and prevented TNF-alpha-induced p65 transactivation activity.
|
|