Ignet

Gene Pair: TXN, TXNIP

Related Sentences

#	PMID	Sentence
1	15128745	Diabetic animals exhibited increased vascular expression of Txnip and reduced thioredoxin activity, which normalized with insulin treatment.
2	15128745	These studies implicate reduced thioredoxin activity through interaction with Txnip as an important mechanism for vascular oxidative stress in diabetes mellitus.
3	20023662	Inflammasome activators such as uric acid crystals induced the dissociation of TXNIP from thioredoxin in a reactive oxygen species (ROS)-sensitive manner and allowed it to bind NLRP3.
4	21615774	The expression of TRX and insulin in islets and plasma SOD and CAT activity were lower, but the expression of TXNIP in islets and plasma MDA were higher, in diabetic compared with normal control rats.
5	21615774	Upregulated expression of TRX and insulin and downregulated expression of TXNIP were observed in probucol-treated diabetic rats.