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PMID |
Sentence |
1 |
10603304
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The expression of both mtDNA (by mtTFA) and nDNA for oxphos and UCP (by NRFs, etc.) is coordinated by a factor called PGC-1.
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2 |
12807871
|
Peroxisome proliferator-activated receptor gamma (PPAR gamma) and PPAR gamma coactivator 1 alpha (PGC-1 alpha) activate mouse UCP1 gene transcription.
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3 |
12807871
|
We show here that human PGC-1 alpha induced the activation of the human UCP1 promoter by PPAR gamma.
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4 |
12807871
|
Adenovirus-mediated expression of human PGC-1 alpha increased the expression of UCP1, respiratory chain proteins, and fatty acid oxidation enzymes in human subcutaneous white adipocytes.
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5 |
12807871
|
The PPAR gamma agonist rosiglitazone potentiated the effect of PGC-1 alpha on UCP1 expression and fatty acid oxidation.
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6 |
12807871
|
UCP1 mRNA induction was shown in vivo by injection of the PGC-1 alpha adenovirus in mouse white fat.
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