Ignet

Gene Pair: CLEC1B, PDPN

Related Sentences

#	PMID	Sentence
1	18215137	The transmembrane protein podoplanin was identified on HEK-293T cells and was demonstrated to mediate both binding of HEK-293T cells to CLEC-2 and HEK-293T cell activation of CLEC-2-transfected DT-40 B-cells.
2	18215137	The present study identifies podoplanin as a ligand for CLEC-2 on renal cells.
3	21781241	The endogenous ligand of CLEC-2 has been identified as podoplanin, which is expressed on the surface of tumour cells and facilitates tumour metastasis by inducing platelet activation.
4	21781241	In the developmental stages, when the primary lymph sac is derived from the cardinal vein, podoplanin activates platelets in lymphatic endothelial cells by binding to CLEC-2, which facilitates blood/lymphatic vessel separation.