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Gene Pair Information
Gene Pair: NPHS1, NOTCH1
Related Sentences
| # | PMID | Sentence |
| 1 | 20522599 | After use of pharmacological modulators or specific shRNA knockdown strategies, inhibition of Notch-1 signaling significantly abrogated VEGF activation and nephrin repression in HG-stressed cells and ameliorated proteinuria in the diabetic kidney. |
| 2 | 20522599 | Our findings suggest that upregulation of Notch-1 signaling in HG-treated renal podocytes induces VEGF expression and subsequent nephrin repression and apoptosis. |