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Gene Pair Information
Gene Pair: NPHS1, TENC1
Related Sentences
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PMID |
Sentence |
1 |
19129671
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Using tensin2-deficient mice (ICGN/Oa strain), we provide evidence that tensin2 is important for glomerular nephrin expression in vivo.
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2 |
19129671
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In heterozygous mice with a single mutated tensin2 allele, nephrin expression was maintained, while albuminuria was not observed.
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3 |
19129671
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In contrast, nephrin expression was impaired, especially in the central zones of glomeruli of homozygous mice (with double mutated tensin2 alleles), even at one week after birth.
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4 |
19129671
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Therefore, we suggested that tensin2 is involved in expression and extension of nephrin, while tensin2 deficiency may result in proteinuria, associated with the loss of slit integrity.
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