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Gene Pair Information

Gene Pair: NPHS1, TENC1

Related Sentences

# PMID Sentence
1 19129671 Using tensin2-deficient mice (ICGN/Oa strain), we provide evidence that tensin2 is important for glomerular nephrin expression in vivo.
2 19129671 In heterozygous mice with a single mutated tensin2 allele, nephrin expression was maintained, while albuminuria was not observed.
3 19129671 In contrast, nephrin expression was impaired, especially in the central zones of glomeruli of homozygous mice (with double mutated tensin2 alleles), even at one week after birth.
4 19129671 Therefore, we suggested that tensin2 is involved in expression and extension of nephrin, while tensin2 deficiency may result in proteinuria, associated with the loss of slit integrity.