Ignet

Gene Pair: TENC1, NPHS1

Related Sentences

#	PMID	Sentence
1	19129671	Using tensin2-deficient mice (ICGN/Oa strain), we provide evidence that tensin2 is important for glomerular nephrin expression in vivo.
2	19129671	In heterozygous mice with a single mutated tensin2 allele, nephrin expression was maintained, while albuminuria was not observed.
3	19129671	In contrast, nephrin expression was impaired, especially in the central zones of glomeruli of homozygous mice (with double mutated tensin2 alleles), even at one week after birth.
4	19129671	Therefore, we suggested that tensin2 is involved in expression and extension of nephrin, while tensin2 deficiency may result in proteinuria, associated with the loss of slit integrity.